Nom du produit:(2S)-2-(bromomethyl)oxetane

IUPAC Name:(2S)-2-(bromomethyl)oxetane

CAS:2198099-00-0
Formule moléculaire:C4H7BrO
Pureté:95%+
Numéro de catalogue:CM422800
Poids moléculaire:151

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Détails du produit

N° CAS:2198099-00-0
Formule moléculaire:C4H7BrO
Point de fusion:-
Code SMILES:BrC[C@@H]1CCO1
Densité:
Numéro de catalogue:CM422800
Poids moléculaire:151
Point d'ébullition:
N° Mdl:MFCD31926893
Stockage:

Category Infos

Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.