Nom du produit:tert-butyl 2-(hydroxymethyl)-1-oxa-5-azaspiro[2.3]hexane-5-carboxylate

IUPAC Name:tert-butyl 2-(hydroxymethyl)-1-oxa-5-azaspiro[2.3]hexane-5-carboxylate

CAS:2167976-93-2
Formule moléculaire:C10H17NO4
Pureté:95%+
Numéro de catalogue:CM350140
Poids moléculaire:215.25

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Détails du produit

N° CAS:2167976-93-2
Formule moléculaire:C10H17NO4
Point de fusion:-
Code SMILES:O=C(N(C1)CC21C(CO)O2)OC(C)(C)C
Densité:
Numéro de catalogue:CM350140
Poids moléculaire:215.25
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Oxiranes
Oxirane is a three-membered ring compound consisting of one oxygen atom and two carbon atoms. Oxirane is present in natural products such as cryptocin, which has anticancer properties, and azidomycin, trienone, and epoxidomycin, which have shown activity against drug-resistant leukemias and AIDS-related lymphomas. Other oxirane containing bioactive molecules have anti-inflammatory, immunosuppressive, and antitumor activities. Oxiranes are a strained ring susceptible to various nucleophilic, ring-opening or rearrangement reactions, so they are considered to be one of the most important intermediates in organic synthesis.

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