Nom du produit:Methyl 2-[5-(hydroxymethyl)-3-methyl-1,2-oxazol-4-yl]benzoate
IUPAC Name:methyl 2-[5-(hydroxymethyl)-3-methyl-1,2-oxazol-4-yl]benzoate
- CAS:2086298-52-2
- Formule moléculaire:C13H13NO4
- Pureté:95%
- Numéro de catalogue:CM1074977
- Poids moléculaire:247.25
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Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2086298-52-2
- Formule moléculaire:C13H13NO4
- Point de fusion:-
- Code SMILES:O=C(OC)C=1C=CC=CC1C=2C(=NOC2CO)C
- Densité:
- Numéro de catalogue:CM1074977
- Poids moléculaire:247.25
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Isoxazoles
- Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.
Column Infos
- Pelabresib
- MorphoSys’ phase 3 study of Pelabresib in myelofibrosis demonstrates statistically significant improvement in spleen volume reduction and strong positive trend in symptom reduction.
Pelabresib (CPI-0610) is an investigational selective small molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. MorphoSys intends to submit for approval in the U.S. and Europe in mid-2024.