Nom du produit:5-(cyclopropylmethyl)-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

IUPAC Name:5-(cyclopropylmethyl)-1-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole

CAS:2079069-46-6
Formule moléculaire:C14H23BN2O2
Pureté:95%+
Numéro de catalogue:CM430407
Poids moléculaire:262.16

Unité d'emballage Stock disponible Prix($) Quantité
CM430407-100mg in stock Žǟţħ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:2079069-46-6
Formule moléculaire:C14H23BN2O2
Point de fusion:-
Code SMILES:CN1N=CC(B2OC(C)(C)C(C)(C)O2)=C1CC1CC1
Densité:
Numéro de catalogue:CM430407
Poids moléculaire:262.16
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos

BTX-A51
Edgewood Oncology announced that the first two patients with metastatic breast cancer were treated with BTX-A51, a multi-specific kinase inhibitor of casein kinase 1 alpha (CK1α) and cyclin-dependent kinases 7 and 9 (CDK7 and CDK9), that synergistically targets master regulators of cancer. BTX-A51 is being evaluated in a Phase 2a study for the treatment of estrogen receptor positive / human epidermal growth factor receptor 2 negative (ER+/HER2-) metastatic breast cancer with and without GATA binding protein 3 (GATA3) mutations.
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