Nom du produit:tert-Butyl (3S)-3-methylazetidine-2-carboxylate hydrochloride
IUPAC Name:tert-butyl (3S)-3-methylazetidine-2-carboxylate hydrochloride
- CAS:2064338-07-2
- Formule moléculaire:C9H18ClNO2
- Pureté:95%+
- Numéro de catalogue:CM460148
- Poids moléculaire:207.7
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:2064338-07-2
- Formule moléculaire:C9H18ClNO2
- Point de fusion:-
- Code SMILES:Cl.C[C@H]1CNC1C(=O)OC(C)(C)C
- Densité:
- Numéro de catalogue:CM460148
- Poids moléculaire:207.7
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Column Infos
- Delgocitinib
- Positive phase 3 head-to-head data results from DELTA FORCE trial comparing delgocitinib cream with alitretinoin capsules in adults with severe chronic hand eczema (CHE). Delgocitinib cream demonstrated a superior reduction in Hand Eczema Severity Index score from baseline to Week 12 compared to alitretinoin capsules as its primary outcome measure.
Delgocitinib cream is an investigational, first-in-class, topical pan-Janus kinase (JAK) inhibitor for CHE. It inhibits the activation of JAK-STAT signaling, which plays a key role in the pathogenesis of CHE.