Nom du produit:methyl 3-[1-(6-phenylpyrimidin-4-yl)azetidine-3-amido]thiophene-2-carboxylate

IUPAC Name:methyl 3-[1-(6-phenylpyrimidin-4-yl)azetidine-3-amido]thiophene-2-carboxylate

CAS:2034286-39-8
Formule moléculaire:C20H18N4O3S
Pureté:95%+
Numéro de catalogue:CM924846
Poids moléculaire:394.45

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Détails du produit

N° CAS:2034286-39-8
Formule moléculaire:C20H18N4O3S
Point de fusion:-
Code SMILES:COC(=O)C1=C(NC(=O)C2CN(C2)C2=CC(=NC=N2)C2=CC=CC=C2)C=CS1
Densité:
Numéro de catalogue:CM924846
Poids moléculaire:394.45
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Thiophenes
Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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