Nom du produit:N-(3-chloro-4-fluorophenyl)-1-(6-phenylpyrimidin-4-yl)azetidine-3-carboxamide
IUPAC Name:N-(3-chloro-4-fluorophenyl)-1-(6-phenylpyrimidin-4-yl)azetidine-3-carboxamide
- CAS:2034285-26-0
- Formule moléculaire:C20H16ClFN4O
- Pureté:95%+
- Numéro de catalogue:CM949405
- Poids moléculaire:382.82
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Détails du produit
- N° CAS:2034285-26-0
- Formule moléculaire:C20H16ClFN4O
- Point de fusion:-
- Code SMILES:FC1=C(Cl)C=C(NC(=O)C2CN(C2)C2=CC(=NC=N2)C2=CC=CC=C2)C=C1
- Densité:
- Numéro de catalogue:CM949405
- Poids moléculaire:382.82
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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