Nom du produit:N-(1H-1,2,3-benzotriazol-5-yl)-1-(6-phenylpyrimidin-4-yl)azetidine-3-carboxamide
IUPAC Name:N-(1H-1,2,3-benzotriazol-5-yl)-1-(6-phenylpyrimidin-4-yl)azetidine-3-carboxamide
- CAS:2034258-44-9
- Formule moléculaire:C20H17N7O
- Pureté:95%+
- Numéro de catalogue:CM940096
- Poids moléculaire:371.4
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Détails du produit
- N° CAS:2034258-44-9
- Formule moléculaire:C20H17N7O
- Point de fusion:-
- Code SMILES:O=C(NC1=CC2=C(NN=N2)C=C1)C1CN(C1)C1=CC(=NC=N1)C1=CC=CC=C1
- Densité:
- Numéro de catalogue:CM940096
- Poids moléculaire:371.4
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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- Benzotriazoles
- Benzotriazole is a bicyclic nitrogen heterocycle formed by the fusion of the benzene ring with the 4,5-positions or the “d” site of 1H-1,2,3-triazole. The benzotriazoles are known as important intermediates in the preparation of organic products such as β-amido ketones, aldehydes, β-ketoesters, ionic liquid, and as reagents for acylation and thioacylation reactions. 1H-Benzotriazoles are also known to exhibit broad spectrum of pharmacological activities. There are numerous benzotriazole-based clinically used drugs in the market for the treatment of various diseases.