cas 1971072-97-5|| where to buy 7-bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione

Nom du produit:7-bromo-3,4-dihydropyrido[2,1-c][1,4]oxazine-1,6-dione

IUPAC Name:7-bromo-1H,3H,4H,6H-pyrido[2,1-c][1,4]oxazine-1,6-dione

: CAS：1971072-97-5; Formule moléculaire：C8H6BrNO3; Pureté：95%+

: Numéro de catalogue：CM425449; Poids moléculaire：244.04

Unité d'emballage	Stock disponible	Prix($)
CM425449-100mg	1-2 Weeks	ľľ
CM425449-250mg	3-4 Weeks	ƚƈŤ
CM425449-1g	3-4 Weeks	ŮǸƚ
CM425449-5g	4-5 Weeks	ľľƿ

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Détails du produit

: N° CAS:1971072-97-5; Formule moléculaire:C8H6BrNO3; Point de fusion:-; Code SMILES:BrC1=CC=C2N(CCOC2=O)C1=O; Densité:

: Numéro de catalogue:CM425449; Poids moléculaire:244.04; Point d'ébullition:; N° Mdl:; Stockage:

Category Infos

: Pyridines; Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.; Pyridine | C5H5N | Pyridine Supplier/Distributor/Manufacturer - Chemenu; Pyridine,Pyridine Wholesale,Pyridine for Sale,Pyridine Supplier,Pyridine Distributor,Pyridine Manufacturer; Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.

Column Infos

: PF-06648671; The Journal of Medicinal Chemistry recently publishes an article titled, “Discovery of Clinical Candidate PF-06648671: A Potent γ-Secretase Modulator for the Treatment of Alzheimer’s Disease”. Amyloid β-peptide (Aβ) accumulation is one of the key hallmarks of Alzheimer’s disease (AD). γ-secretase cleaves the amyloid precursor protein (APP) into pathologically relevant Aβs, and has been widely studied as a potential target for the treatment of AD.
Pfizer‘s PF-06648671 is a Gamma secretase modulator (GSM) targeting APP processing. It is found to have excellent central exposure in human and robust reduction of amyloidogenic forms (Aβ42) in cerebrospinal fluid (CSF).

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