Nom du produit:(2S,4R)-1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-((S)-1-(4-(4-methylthiazol-5-yl)phenyl)ethyl)pyrrolidine-2-carboxamide hydrochloride

IUPAC Name:(2S,4R)-1-[(2S)-2-amino-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide hydrochloride

CAS:1948273-03-7
Formule moléculaire:C23H33ClN4O3S
Pureté:95%+
Numéro de catalogue:CM362099
Poids moléculaire:481.05

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CM362099-250mg in stock ȃľ
CM362099-1g in stock ǪŹƥ
CM362099-5g in stock ƥƥǪ
CM362099-25g in stock ľƿǪȃ

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Détails du produit

N° CAS:1948273-03-7
Formule moléculaire:C23H33ClN4O3S
Point de fusion:-
Code SMILES:O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)N[C@H](C2=CC=C(C3=C(C)N=CS3)C=C2)C.[H]Cl
Densité:
Numéro de catalogue:CM362099
Poids moléculaire:481.05
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

KT-333
Kymera shared new clinical data from its ongoing KT-333 Phase 1 trial. KT-333, a first-in-class, potent, highly selective, heterobifunctional small molecule degrader of STAT3, demonstrated antitumor responses in hematological malignancies with high unmet need, including relapsed/refractory classic Hodgkin’s lymphoma (cHL), cutaneous T-cell lymphoma (CTCL), and NK-cell lymphoma, at doses that were well-tolerated.
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