Nom du produit:(1S)-2,2-difluorocyclopropanecarboxylic acid

IUPAC Name:(1S)-2,2-difluorocyclopropane-1-carboxylic acid

CAS:1883301-82-3
Formule moléculaire:C4H4F2O2
Pureté:95%+
Numéro de catalogue:CM326418
Poids moléculaire:122.07

Unité d'emballage Stock disponible Prix($) Quantité
CM326418-10g in stock ǕȦȌƱ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1883301-82-3
Formule moléculaire:C4H4F2O2
Point de fusion:-
Code SMILES:O=C([C@H]1C(F)(F)C1)O
Densité:
Numéro de catalogue:CM326418
Poids moléculaire:122.07
Point d'ébullition:
N° Mdl:MFCD30471588
Stockage:Store at 2°C~8°C

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Pharmaceutical intermediates, bulk products, chiral, achiral, heterocycles, metal catalysts, amino acids, peptides, benzene, pyridine, pyrazine, triazine, piperidine, piperazine, morpholine, imidazoline, cyclopropane, indole, benzotriazole, anthranil, quinoline, naphthalene, boronic compounds, fluorination, oxidation, rearrangement reaction
Chemenu product lines cover amino acids and peptides, heterocyclic compounds, alkanes and aromatic compounds, carbohydrates, alcohols, aldehydes & ketones, pyridazines, metal catalysts and other pharmaceutical intermediates. For more custom organic synthesis, please contact us for a quote.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Fluorinated compounds
Fluorinated compounds refers to organic or inorganic compounds containing fluorine.
Brepocitinib
Priovant Therapeutics announced positive Phase 2 NEPTUNE study results for brepocitinib in Non-Infectious Uveitis (NIU), showing strongest efficacy data in NIU observed to date. Brepocitinib selectively binds to and inhibits the activation of TYK2 and JAK1, thereby disrupting TYK2 and JAK-1-dependent cytokine signaling. This may reduce inflammatory responses and prevent inflammation-induced damage caused by certain immunological diseases.