Nom du produit:tert-Butyl 5-benzyl-octahydropyrrolo-[3,4-c]pyrrole-2-carboxylate

IUPAC Name:tert-butyl 5-benzyl-octahydropyrrolo[3,4-c]pyrrole-2-carboxylate

CAS:186202-73-3
Formule moléculaire:C18H26N2O2
Pureté:97%
Numéro de catalogue:CM197623
Poids moléculaire:302.42

Unité d'emballage Stock disponible Prix($) Quantité
CM197623-250mg in stock ȷɅ
CM197623-1g in stock ƙǧƋ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:186202-73-3
Formule moléculaire:C18H26N2O2
Point de fusion:-
Code SMILES:O=C(N1CC(CN(CC2=CC=CC=C2)C3)C3C1)OC(C)(C)C
Densité:
Numéro de catalogue:CM197623
Poids moléculaire:302.42
Point d'ébullition:
N° Mdl:MFCD18909636
Stockage:Store at 2-8°C.

Category Infos

Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.

Column Infos

Seltorexant
Johnson & Johnson pivotal study of Seltorexant shows statistically significant and clinically meaningful improvement in depressive symptoms and sleep disturbance outcomes. Seltorexant meets all primary and secondary endpoints in the pivotal Phase 3 MDD3001 clinical trial of adult and elderly patients with major depressive disorder (MDD) with insomnia symptoms.
Orexin signaling pathways are found to be associated with depression and anxiety. Orexin neurons receive and transmit signals throughout the central nervous system (CNS) that are modulated by their specific receptors (OX1R, OX2R). Seltorexant is an investigational first-in-class selective antagonist of ORX2 receptor. It is developed as an adjunctive therapy for MDD and for the treatment of insomnia disorder.

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