Nom du produit:5-fluorothiophene-2-carbaldehyde [4-(difluoromethyl)-6-(2-furyl)pyrimidin-2-yl]hydrazone

IUPAC Name:4-(difluoromethyl)-2-{2-[(5-fluorothiophen-2-yl)methylidene]hydrazin-1-yl}-6-(furan-2-yl)pyrimidine

CAS:1855926-76-9
Formule moléculaire:C14H9F3N4OS
Pureté:95%+
Numéro de catalogue:CM633659
Poids moléculaire:338.31

Unité d'emballage Stock disponible Prix($) Quantité

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Détails du produit

N° CAS:1855926-76-9
Formule moléculaire:C14H9F3N4OS
Point de fusion:-
Code SMILES:FC(F)C1=CC(=NC(NN=CC2=CC=C(F)S2)=N1)C1=CC=CO1
Densité:
Numéro de catalogue:CM633659
Poids moléculaire:338.31
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Furans
Furan is a cyclic flammable liquid compound C4H4O that is obtained from wood oils of pines or made synthetically and is used especially in organic synthesis. Furan is aromatic because a pair of lone pair electrons of the oxygen atom in its molecule forms a large π bond in the plane of the conjugated orbital, making a total of 6 electrons in the plane of the conjugated plane, conforming to the 4n+2 structure. Aromaticity makes furan have the property of easy substitution and difficult addition. The other lone pair of electrons in oxygen stretches out. The oxygen atom itself conforms to sp2 hybridization. Due to the presence of the aromatic ring, the chemical behavior of furan is not very similar to that of other unsaturated heterocycles. The oxygen in the aromatic ring has an electron-donating effect, so the electrophilic substitution reactivity of furan is stronger than that of benzene.
Furan | C4H4O | Where to Buy Furans-Chemenu
Furane | Furanes | Furfuran | Furan | C4H4O | Furan Synthesis | Where to Buy Furans
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Thiophenes
Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.
Pyrimidines
Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

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