Nom du produit:1'-(2-Bromoethyl)spiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one

IUPAC Name:1'-(2-bromoethyl)-1',2'-dihydrospiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-2'-one

CAS:1818847-40-3
Formule moléculaire:C11H11BrN2O
Pureté:95%+
Numéro de catalogue:CM212189
Poids moléculaire:267.13

Unité d'emballage Stock disponible Prix($) Quantité
CM212189-250mg in stock ƴħǙ
CM212189-1g in stock ħŌƴ
CM212189-5g in stock ŮŤŌ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1818847-40-3
Formule moléculaire:C11H11BrN2O
Point de fusion:-
Code SMILES:O=C1N(CCBr)C2=NC=CC=C2C31CC3
Densité:
Numéro de catalogue:CM212189
Poids moléculaire:267.13
Point d'ébullition:
N° Mdl:MFCD29060185
Stockage:

Category Infos

Azaindoles
Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research. Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research.Azaindole
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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