Nom du produit:(1-Aminocyclobutyl)methanol

IUPAC Name:(1-aminocyclobutyl)methanol

CAS:180205-34-9
Formule moléculaire:C5H11NO
Pureté:95%+
Numéro de catalogue:CM201973
Poids moléculaire:101.15

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Détails du produit

N° CAS:180205-34-9
Formule moléculaire:C5H11NO
Point de fusion:-
Code SMILES:NC1(CO)CCC1
Densité:
Numéro de catalogue:CM201973
Poids moléculaire:101.15
Point d'ébullition:166.9±13.0°C at 760 mmHg
N° Mdl:MFCD11858293
Stockage:Keep in dark place, store at 2-8°C.

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Pharmaceutical intermediates, bulk products, chiral, achiral, heterocycles, metal catalysts, amino acids, peptides, benzene, pyridine, pyrazine, triazine, piperidine, piperazine, morpholine, imidazoline, cyclopropane, indole, benzotriazole, anthranil, quinoline, naphthalene, boronic compounds, fluorination, oxidation, rearrangement reaction
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Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.

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Nerandomilast
Boehringer’s nerandomilast meets primary endpoint in pivotal phase-III FIBRONEER™-IPF study.
Nerandomilast (BI 1015550) is an investigational oral, preferential inhibitor of phosphodiesterase 4B (PDE4B) that is being studied as a potential treatment for idiopathic pulmonary fibrosis (IPF) and progressive pulmonary fibrosis (PPF). This compound is an investigational agent and has not been approved for use. Nerandomilast was granted FDA Breakthrough Therapy Designation for the treatment of IPF in February 2022.

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