Nom du produit:2-(1H-1,2,3-benzotriazol-1-yl)-N-(2-{imidazo[1,2-a]pyridin-2-yl}phenyl)acetamide
IUPAC Name:2-(1H-1,2,3-benzotriazol-1-yl)-N-(2-{imidazo[1,2-a]pyridin-2-yl}phenyl)acetamide
- CAS:1788948-68-4
- Formule moléculaire:C21H16N6O
- Pureté:95%+
- Numéro de catalogue:CM616503
- Poids moléculaire:368.4
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Détails du produit
- N° CAS:1788948-68-4
- Formule moléculaire:C21H16N6O
- Point de fusion:-
- Code SMILES:O=C(CN1N=NC2=C1C=CC=C2)NC1=C(C=CC=C1)C1=CN2C=CC=CC2=N1
- Densité:
- Numéro de catalogue:CM616503
- Poids moléculaire:368.4
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Imidazopyridines
- With four imidazopyridine-containing drugs and one pyrazolopyridine-containing drug on the market, bicyclic pyridines containing ring-junction nitrogen are privileged structures in medicinal chemistry. With two nitrogen atoms with potential to serve as hydrogen bond acceptors, imidazopyridines and pyrazolopyridines may boost binding to target proteins and elevate potency. In addition, these structures have found utility in FBDD, covalent inhibitors, reducing metabolic liabilities, and creating novel chemical space and intellectual properties. With many of the advanced intermediates now commercially available, they will find more and more applications in drug discovery.
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- Benzotriazoles
- Benzotriazole is a bicyclic nitrogen heterocycle formed by the fusion of the benzene ring with the 4,5-positions or the “d” site of 1H-1,2,3-triazole. The benzotriazoles are known as important intermediates in the preparation of organic products such as β-amido ketones, aldehydes, β-ketoesters, ionic liquid, and as reagents for acylation and thioacylation reactions. 1H-Benzotriazoles are also known to exhibit broad spectrum of pharmacological activities. There are numerous benzotriazole-based clinically used drugs in the market for the treatment of various diseases.