Nom du produit:(R)-1,1,1-Trifluoropropan-2-amine hydrochloride
IUPAC Name:(2R)-1,1,1-trifluoropropan-2-amine hydrochloride
- CAS:177469-12-4
- Formule moléculaire:C3H7ClF3N
- Pureté:95%+
- Numéro de catalogue:CM250388
- Poids moléculaire:149.54
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:177469-12-4
- Formule moléculaire:C3H7ClF3N
- Point de fusion:-
- Code SMILES:C[C@@H](N)C(F)(F)F.[H]Cl
- Densité:
- Numéro de catalogue:CM250388
- Poids moléculaire:149.54
- Point d'ébullition:116°C at 760 mmHg
- N° Mdl:MFCD07779095
- Stockage:Store at room temperature
Category Infos
- New
- Custom Organic Synthesis,Where to Buy Chemical Building Blocks - Chemenu
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- Fluorinated Compounds
- Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Column Infos
- Fluorinated compounds
- Fluorinated compounds refers to organic or inorganic compounds containing fluorine.
- Vorasidenib
- Servier presented the latest clinical data on the IDH1/2 inhibitor vorasidenib (AG-881) in the treatment of IDH-mutated diffuse glioma at the 28th Annual Meeting of the Society of Neuro-Oncology (SNO). Blinded independent radiology committee evaluation showed that vorasidenib significantly reduced tumor growth and not only preserved the patient's quality of life, but also stabilized neurocognitive function and controlled epilepsy. Based on these results, the company plans to submit a new drug application for vorasidenib to the U.S. FDA by the end of 2023 for the treatment of IDH-mutated diffuse glioma. Vorasidenib is an oral, brain-penetrating and selective dual inhibitor under development that can inhibit mutated IDH1/2 proteins and is a potential "first-in-class" drug. It has received breakthrough therapy designation from the FDA.
Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.