Nom du produit:2-Cyclopropyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazoline

IUPAC Name:2-cyclopropyl-4-(piperazin-1-yl)-5,6,7,8-tetrahydroquinazoline

CAS:1708013-37-9
Formule moléculaire:C15H22N4
Pureté:95%+
Numéro de catalogue:CM211686
Poids moléculaire:258.37

Unité d'emballage Stock disponible Prix($) Quantité
CM211686-1g 1-2 Weeks ǤůĽ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1708013-37-9
Formule moléculaire:C15H22N4
Point de fusion:-
Code SMILES:C1(C2CC2)=NC(N3CCNCC3)=C4CCCCC4=N1
Densité:
Numéro de catalogue:CM211686
Poids moléculaire:258.37
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Quinazolines
Quinazolines belong to heterocyclic chemistry, also known as 1,3-naphthalenes. The backbone consists of two six-membered aromatic rings fused to each other, with two nitrogen atoms at positions 1 and 3 on the backbone. The presence of these two nitrogen atoms in quinazoline increases its importance in pharmaceutical and biological reactions. Quinazolines and their derivatives are among the most important heterocyclic compounds due to their diverse chemical reactivity and important range of biological activities.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

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