Nom du produit:2,7-Bis(trifluoromethyl)-9H-carbazole

IUPAC Name:2,7-bis(trifluoromethyl)-9H-carbazole

CAS:1657076-40-8
Formule moléculaire:C14H7F6N
Pureté:98%
Numéro de catalogue:CM338650
Poids moléculaire:303.20

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Détails du produit

N° CAS:1657076-40-8
Formule moléculaire:C14H7F6N
Point de fusion:-
Code SMILES:FC(C1=CC2=C(C=C1)C3=C(C=C(C(F)(F)F)C=C3)N2)(F)F
Densité:
Numéro de catalogue:CM338650
Poids moléculaire:303.20
Point d'ébullition:
N° Mdl:
Stockage:2-8°C

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Carbazoles
Carbazoles are an important class of nitrogen-containing heterocycles with a planar tricyclic skeleton consisting of two benzene rings fused on both sides of the central pyrrole ring, with a large aromatic system and a central nitrogen atom, showing broad of electron delocalization. The structure of this compound is based on the indole structure, but in which a second benzene ring is fused to a five-membered ring at positions 2-3 of the indole. Carbazole structural motifs are widely found in, but not limited to, a large number of natural alkaloids of plant or bacterial origin. Since many of these alkaloids are medically useful, exhibit a fairly wide range of biological activities (anticancer, anti-HIV, antibacterial, anti-Alzheimer's disease, anticoagulant, analgesic, antiepileptic, antidiabetic, antioxidant, etc.). Medicinal chemistry also uses carbazole motifs in synthetic drugs to combat hypertension, heart disease, and hepatitis C virus replication.
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