cas 1630906-91-0|| where to buy 1,1-difluoro-5-azaspiro[2.3]hexane hydrochloride

Nom du produit:1,1-difluoro-5-azaspiro[2.3]hexane hydrochloride

IUPAC Name:1,1-difluoro-5-azaspiro[2.3]hexane hydrochloride

Unité d'emballage	Stock disponible	Prix($)	Quantité
CM107264-10g	in stock	ȋǠȤǆ

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: N° CAS:1630906-91-0; Formule moléculaire:C5H8ClF2N; Point de fusion:-; Code SMILES:FC1(F)CC12CNC2.[H]Cl; Densité:

: Numéro de catalogue:CM107264; Poids moléculaire:155.57; Point d'ébullition:; N° Mdl:; Stockage:

: Azetidines; Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.; Where to buy Azetidines; Where to buy ADC-Cytotoxins? Chemenu Provide Azetidines with high quality and competitive price. Contact us Now.

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

: Spiro Compounds; A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.

: Fluorinated compounds; Fluorinated compounds refers to organic or inorganic compounds containing fluorine.