Nom du produit:2-Cyclopropyl-2,6-diazaspiro[3.3]heptane bis(2,2,2-trifluoroacetate)

IUPAC Name:2-cyclopropyl-2,6-diazaspiro[3.3]heptane; bis(trifluoroacetic acid)

CAS:1609407-83-1
Formule moléculaire:C12H16F6N2O4
Pureté:95%+
Numéro de catalogue:CM210668
Poids moléculaire:366.26

Unité d'emballage Stock disponible Prix($) Quantité
CM210668-250mg in stock ǜȐŵ
CM210668-1g in stock Ȑȡũȡ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1609407-83-1
Formule moléculaire:C12H16F6N2O4
Point de fusion:-
Code SMILES:O=C(O)C(F)(F)F.O=C(O)C(F)(F)F.N1(C2CC2)CC3(CNC3)C1
Densité:
Numéro de catalogue:CM210668
Poids moléculaire:366.26
Point d'ébullition:
N° Mdl:MFCD28024795
Stockage:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Fluorinated compounds
Fluorinated compounds refers to organic or inorganic compounds containing fluorine.