Nom du produit:5,6-Dimethyl-2,3-dihydropyrazine
IUPAC Name:5,6-dimethyl-2,3-dihydropyrazine
- CAS：15986-92-2
- Formule moléculaire：C6H10N2
- Pureté：95%
- Numéro de catalogue：CM168915
- Poids moléculaire：110.16
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:15986-92-2
- Formule moléculaire:C6H10N2
- Point de fusion:-
- Code SMILES:CC1=NCCN=C1C
- Densité:
- Numéro de catalogue:CM168915
- Poids moléculaire:110.16
- Point d'ébullition:
- N° Mdl:MFCD00129688
- Stockage:
Category Infos
- Pyrazines
- Pyrazine is a heterocyclic aromatic organic compound with chemical formula C4H4N2. The marketed pyrazine drugs are mainly distributed in the field of anti-tumor and anti-infection. In recent years, there have been many new drugs in various fields, and there are some new target drugs worthy of attention.
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Column Infos
- LEI-515
- The recent publication titles “Structure–Activity Relationship Studies of Aryl Sulfoxides as Reversible Monoacylglycerol Lipase Inhibitors”. Monoacylglycerol lipase (MAGL) is the critical enzyme responsible for the hydrolysis of endocannabinoid 2-arachidonoylglycerol (2-AG) to arachidonate and glycerol, contributing to the inflammatory cascade in the CNS. MAGL inhibition provides various potential therapeutic opportunities, including inflammation-induced tissue injury, pain, multiple sclerosis, and cancer.
LEI-515 is an aryl sulfoxide, and a peripherally restricted, covalent reversible MAGL inhibitor. LEI-515 increases 2-AG levels in the periphery and reduces neuropathic pain and inflammation, without inducing CNS adverse effects or physical dependence.
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