Nom du produit:1-(3-Cyclopropyl-1,2,4-thiadiazol-5-yl)piperazine
IUPAC Name:1-(3-cyclopropyl-1,2,4-thiadiazol-5-yl)piperazine
- CAS：1489486-20-5
- Formule moléculaire：C9H14N4S
- Pureté：95%+
- Numéro de catalogue：CM335803
- Poids moléculaire：210.3
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1489486-20-5
- Formule moléculaire:C9H14N4S
- Point de fusion:-
- Code SMILES:N1(C2=NC(C3CC3)=NS2)CCNCC1
- Densité:
- Numéro de catalogue:CM335803
- Poids moléculaire:210.3
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Piperazines
- Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
- Thiadiazoles
- Thiadiazoles are a subfamily of azoles. Structurally, they are five-membered heterocyclic compounds containing two nitrogen atoms and one sulfur atom, and two double bonds, forming an aromatic ring. Depending on the relative positions of the heteroatoms, there are four possible structures; these forms do not interconvert and are therefore structural isomers rather than tautomers. These compounds themselves are rarely synthesized and have no particular utility, however, compounds that use them as structural motifs are fairly common in pharmacology.
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