Nom du produit:3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine;2,2,2-trifluoroacetic acid

IUPAC Name:3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine; trifluoroacetic acid

CAS:1458630-17-5
Formule moléculaire:C18H17F3N6O2
Pureté:95%+
Numéro de catalogue:CM759826
Poids moléculaire:406.37

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Détails du produit

N° CAS:1458630-17-5
Formule moléculaire:C18H17F3N6O2
Point de fusion:-
Code SMILES:OC(=O)C(F)(F)F.CCCNC1=NN2C(C=C1)=NC=C2C1=CC=C2NN=CC2=C1
Densité:
Numéro de catalogue:CM759826
Poids moléculaire:406.37
Point d'ébullition:
N° Mdl:MFCD24849399
Stockage:

Category Infos

Indazoles
Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.
Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.