Nom du produit:2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
IUPAC Name:2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one
- CAS:1449598-86-0
- Formule moléculaire:C8H4ClFN2O
- Pureté:95%+
- Numéro de catalogue:CM337294
- Poids moléculaire:198.58
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1449598-86-0
- Formule moléculaire:C8H4ClFN2O
- Point de fusion:-
- Code SMILES:O=C1C=C(Cl)N=C2N1C=C(F)C=C2
- Densité:
- Numéro de catalogue:CM337294
- Poids moléculaire:198.58
- Point d'ébullition:
- N° Mdl:MFCD28659052
- Stockage:
Column Infos
- Risdiplam
- As the first approved small molecule splicing modifier drug, Risdiplam (Evrysdi) is granted approval by the European Commission to expand the EU marketing authorization. This extension now includes infants with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies from birth to below two months. Type 1 spinal muscular atrophy (SMA) is a rare, progressive neuromuscular disease and a leading genetic factor of infant mortality, that is caused by low levels of functional survival of motor neuron (SMN) protein. Risdiplam modifies SMN2 pre-messenger RNA splicing and increases levels of functional SMN protein in both the central nervous system and peripheral organs.