Nom du produit:2-Chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

IUPAC Name:2-chloro-7-fluoro-4H-pyrido[1,2-a]pyrimidin-4-one

CAS:1449598-86-0
Formule moléculaire:C8H4ClFN2O
Pureté:95%+
Numéro de catalogue:CM337294
Poids moléculaire:198.58

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Détails du produit

N° CAS:1449598-86-0
Formule moléculaire:C8H4ClFN2O
Point de fusion:-
Code SMILES:O=C1C=C(Cl)N=C2N1C=C(F)C=C2
Densité:
Numéro de catalogue:CM337294
Poids moléculaire:198.58
Point d'ébullition:
N° Mdl:MFCD28659052
Stockage:

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Risdiplam
As the first approved small molecule splicing modifier drug, Risdiplam (Evrysdi) is granted approval by the European Commission to expand the EU marketing authorization. This extension now includes infants with a clinical diagnosis of SMA Type 1, Type 2 or Type 3 or with one to four SMN2 copies from birth to below two months. Type 1 spinal muscular atrophy (SMA) is a rare, progressive neuromuscular disease and a leading genetic factor of infant mortality, that is caused by low levels of functional survival of motor neuron (SMN) protein. Risdiplam modifies SMN2 pre-messenger RNA splicing and increases levels of functional SMN protein in both the central nervous system and peripheral organs.