Nom du produit:methyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxetane-3-carboxylate

IUPAC Name:methyl 3-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]oxetane-3-carboxylate

CAS:1423702-68-4
Formule moléculaire:C17H23BO5
Pureté:95%+
Numéro de catalogue:CM1018226
Poids moléculaire:318.18

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CM1018226-100mg in stock ǕǯƏ
CM1018226-250mg in stock ňƅŔ
CM1018226-500mg in stock ƏŔȀ
CM1018226-1g 1-2 Weeks ȀŔǕǯ
CM1018226-5g 1-2 Weeks Ǖƻƅǯ

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Détails du produit

N° CAS:1423702-68-4
Formule moléculaire:C17H23BO5
Point de fusion:-
Code SMILES:COC(=O)C1(COC1)C1=CC=C(C=C1)B1OC(C)(C)C(C)(C)O1
Densité:
Numéro de catalogue:CM1018226
Poids moléculaire:318.18
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.

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