Nom du produit:Ethyl 2',4'-dichloro-5'-oxo-6',8'-dihydro-5'H-spiro[cyclobutane-1,7'-quinoline]-3'-carboxylate

IUPAC Name:ethyl 2',4'-dichloro-5'-oxo-6',8'-dihydro-5'H-spiro[cyclobutane-1,7'-quinoline]-3'-carboxylate

CAS:1384265-01-3
Formule moléculaire:C15H15Cl2NO3
Pureté:97%
Numéro de catalogue:CM208668
Poids moléculaire:328.19

Unité d'emballage Stock disponible Prix($) Quantité
CM208668-1g in stock ǪǙǪIJ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1384265-01-3
Formule moléculaire:C15H15Cl2NO3
Point de fusion:-
Code SMILES:O=C(C1=C(Cl)C(C(C2)=O)=C(N=C1Cl)CC32CCC3)OCC
Densité:
Numéro de catalogue:CM208668
Poids moléculaire:328.19
Point d'ébullition:
N° Mdl:MFCD22573755
Stockage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Cyclobutanes
The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.
Tetrahydroquinolines
Tetrahydroquinoline is one of the most important simple nitrogen heterocycles, widely found in nature and in a variety of pharmacologically active compounds. Tetrahydroquinoline is an important structure for the synthesis of various biologically active derivatives.

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