cas 1380089-99-5|| where to buy 1,1-Dimethylethyl (4S)-5,6-dihydro-1-methyl-6-oxo-4H-isoxazolo[5,4-d][2]benzazepine-4-acetate

Nom du produit:1,1-Dimethylethyl (4S)-5,6-dihydro-1-methyl-6-oxo-4H-isoxazolo[5,4-d][2]benzazepine-4-acetate

IUPAC Name:tert-butyl 2-[(7S)-3-methyl-9-oxo-5-oxa-4,8-diazatricyclo[8.4.0.0²,⁶]tetradeca-1(14),2(6),3,10,12-pentaen-7-yl]acetate

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: N° CAS:1380089-99-5; Formule moléculaire:C18H20N2O4; Point de fusion:-; Code SMILES:CC=1C=2C=3C(C(=O)N[C@@H](CC(OC(C)(C)C)=O)C2ON1)=CC=CC3; Densité:

: Numéro de catalogue:CM1074974; Poids moléculaire:328.37; Point d'ébullition:; N° Mdl:; Stockage:

: Isoxazoles; Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.

: Pelabresib; MorphoSys’ phase 3 study of Pelabresib in myelofibrosis demonstrates statistically significant improvement in spleen volume reduction and strong positive trend in symptom reduction.
Pelabresib (CPI-0610) is an investigational selective small molecule designed to promote anti-tumor activity by inhibiting the function of bromodomain and extra-terminal domain (BET) proteins to decrease the expression of abnormally expressed genes in cancer. MorphoSys intends to submit for approval in the U.S. and Europe in mid-2024.