Nom du produit:7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolin-1-one
IUPAC Name:7-(trifluoromethyl)-1,2,3,4-tetrahydroisoquinolin-1-one
- CAS：1365759-12-1
- Formule moléculaire：C10H8F3NO
- Pureté：97%
- Numéro de catalogue：CM106712
- Poids moléculaire：215.18
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1365759-12-1
- Formule moléculaire:C10H8F3NO
- Point de fusion:-
- Code SMILES:O=C1NCCC2=C1C=C(C(F)(F)F)C=C2
- Densité:
- Numéro de catalogue:CM106712
- Poids moléculaire:215.18
- Point d'ébullition:
- N° Mdl:
- Stockage:
Category Infos
- Fluorinated Compounds
- Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
- Tetrahydroisoquinolines
- Tetrahydroisoquinoline is an organic compound with the chemical formula C9H11N. It is classified as a secondary amine, obtained from isoquinoline by hydrogenation. The tetrahydroisoquinoline moiety forms the backbone of several natural, synthetic and semi-synthetic drugs approved for the treatment of cancer, pain, gout and various neurodegenerative diseases.
Column Infos
- Quinolines
- Quinolines are an important class of biologically active heterocyclic compounds, and their derivatives usually exhibit a variety of biological activities. They can be used as antimalarial drugs and in the preparation of other antimalarial drugs. Other important activities of quinoline derivatives include inhibitory activity against EGFR-TK and antipsychotic activity. Futhermore, quinoline scaffolds are present in various drug molecules, including the antimalarial drugs aablaquine, chloroquine, mefloquine and primaquine, and the antibacterial agents gatifloxacin, levofloxacin, and moxifloxacin.
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