Nom du produit:6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester

IUPAC Name:tert-butyl 6-oxo-2,7,11-triazadispiro[3.0.4⁵.3⁴]dodecane-2-carboxylate

CAS:1341037-07-7
Formule moléculaire:C14H23N3O3
Pureté:97%
Numéro de catalogue:CM207996
Poids moléculaire:281.36

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CM207996-1g in stock ĜĜţŁ

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Détails du produit

N° CAS:1341037-07-7
Formule moléculaire:C14H23N3O3
Point de fusion:-
Code SMILES:O=C(N1CC2(C3(CNC2)C(NCC3)=O)C1)OC(C)(C)C
Densité:
Numéro de catalogue:CM207996
Poids moléculaire:281.36
Point d'ébullition:
N° Mdl:MFCD21362264
Stockage:

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Product Other Information

Product Overview 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester (6-Oxo-TBD) is an organic compound that has been studied extensively for its potential applications in scientific research. 6-Oxo-TBD has been found to have a variety of biochemical and physiological effects, and its ability to interact with biological systems makes it a valuable tool for use in experiments.
Synthesis and Application 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester is synthesized through a multi-step process. The first step involves the formation of an oxazoline intermediate from the reaction of 2-bromo-3-methyl-1-pentanone with 2-amino-2-methyl-1-propanol. This intermediate is then reacted with tert-butyl bromide to form the tert-butyl ester of 6-oxo-TBD. This reaction is carried out in the presence of a strong base such as sodium hydroxide or potassium hydroxide. The final product is then purified using a combination of column chromatography and recrystallization. 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester has been studied extensively for its potential applications in scientific research. It has been used as a tool to study the effects of small molecules on biological systems, as well as to study the effects of drugs on the body. 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester has also been used to study the effects of hormones and other small molecules on gene expression. Additionally, it has been used to study the effects of environmental toxins on the body. 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester has also been used to study the effects of various drugs on the body, as well as to study the effects of various drugs on the brain.
Future Directions The potential future applications of 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester are numerous. One potential application is in the development of new drugs for the treatment of various diseases. 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester could also be used to study the effects of environmental toxins on the body. Additionally, 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester could be used to study the effects of various hormones and neurotransmitters on gene expression. Finally, 6-Oxo-2,7,11-triaza-dispiro[3.0.4.3]dodecane-2-carboxylic acid tert-butyl ester could be used to study the effects of various drugs on the brain.