Nom du produit:1-(2-Chloro-5-fluoropyrimidin-4-yl)azepane
IUPAC Name:1-(2-chloro-5-fluoropyrimidin-4-yl)azepane
- CAS：1338495-03-6
- Formule moléculaire：C10H13ClFN3
- Pureté：97%
- Numéro de catalogue：CM290460
- Poids moléculaire：229.68
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1338495-03-6
- Formule moléculaire:C10H13ClFN3
- Point de fusion:-
- Code SMILES:FC1=CN=C(Cl)N=C1N2CCCCCC2
- Densité:
- Numéro de catalogue:CM290460
- Poids moléculaire:229.68
- Point d'ébullition:
- N° Mdl:MFCD20441386
- Stockage:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azepanes
- The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.
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