Nom du produit:4-([1,1'-Biphenyl]-4-carbonyl)-8-benzyl-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid

IUPAC Name:8-benzyl-4-{[1,1'-biphenyl]-4-carbonyl}-1-oxa-4,8-diazaspiro[4.5]decane-3-carboxylic acid

CAS:1326808-51-8
Formule moléculaire:C28H28N2O4
Pureté:97%
Numéro de catalogue:CM207527
Poids moléculaire:456.54

Unité d'emballage Stock disponible Prix($) Quantité

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1326808-51-8
Formule moléculaire:C28H28N2O4
Point de fusion:-
Code SMILES:O=C(C1COC2(CCN(CC3=CC=CC=C3)CC2)N1C(C4=CC=C(C5=CC=CC=C5)C=C4)=O)O
Densité:
Numéro de catalogue:CM207527
Poids moléculaire:456.54
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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Oxazolidines
Oxazolidines are five-membered ring compounds consisting of three carbons, nitrogen and oxygen. Oxygen and nitrogen are in the 1 and 3 positions, respectively. Oxazolidine is in general yellow or slightly yellow, alkaline liquid or solid, easily hydrolyzed by water or alcohol. It is insoluble in water (or hydrolyzed); soluble in benzene and chloroform. Oxazolidine derivatives are five-membered cyclic compounds containing at least one oxygen and nitrogen in their molecular structure. Oxazolidine derivatives are known to possess various therapeutic activities, such as anticancer and antibiotic properties.