Nom du produit:5'-Bromospiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one
IUPAC Name:5'-bromo-1',2'-dihydrospiro[cyclopropane-1,3'-pyrrolo[2,3-b]pyridin]-2'-one
- CAS：1263279-55-5
- Formule moléculaire：C9H7BrN2O
- Pureté：95%+
- Numéro de catalogue：CM206939
- Poids moléculaire：239.07
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1263279-55-5
- Formule moléculaire:C9H7BrN2O
- Point de fusion:-
- Code SMILES:O=C1NC2=NC=C(Br)C=C2C31CC3
- Densité:
- Numéro de catalogue:CM206939
- Poids moléculaire:239.07
- Point d'ébullition:
- N° Mdl:MFCD22422694
- Stockage:
Category Infos
- Azaindoles
- Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research. Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research.Azaindole
- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
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