Nom du produit:3-(4-(Tributylstannyl)thiazol-2-yl)oxetan-3-ol

IUPAC Name:3-[4-(tributylstannyl)-1,3-thiazol-2-yl]oxetan-3-ol

CAS:1245816-13-0
Formule moléculaire:C18H33NO2SSn
Pureté:95%
Numéro de catalogue:CM284084
Poids moléculaire:446.24

Unité d'emballage Stock disponible Prix($) Quantité
CM284084-250mg in stock źƞƄ
CM284084-500mg in stock ƞƄƻ
CM284084-1g in stock ǯŔƞ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1245816-13-0
Formule moléculaire:C18H33NO2SSn
Point de fusion:-
Code SMILES:OC1(C2=NC([Sn](CCCC)(CCCC)CCCC)=CS2)COC1
Densité:
Numéro de catalogue:CM284084
Poids moléculaire:446.24
Point d'ébullition:
N° Mdl:MFCD16140389
Stockage:

Category Infos

Thiazoles
Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Oxetanes
Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.