Nom du produit:tert-butyl3-(5-chloropyrimidin-2-yl)azetidine-1-carboxylate
IUPAC Name:tert-butyl 3-(5-chloropyrimidin-2-yl)azetidine-1-carboxylate
- CAS:1236861-68-9
- Formule moléculaire:C12H16ClN3O2
- Pureté:95%+
- Numéro de catalogue:CM753140
- Poids moléculaire:269.73
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Détails du produit
- N° CAS:1236861-68-9
- Formule moléculaire:C12H16ClN3O2
- Point de fusion:-
- Code SMILES:CC(C)(C)OC(=O)N1CC(C1)C1=NC=C(Cl)C=N1
- Densité:
- Numéro de catalogue:CM753140
- Poids moléculaire:269.73
- Point d'ébullition:
- N° Mdl:MFCD27998409
- Stockage:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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