cas 1226427-48-0|| where to buy 2-{[2-(azepan-1-yl)-6-methylpyrimidin-4-yl]oxy}-N-(4-chloro-2-fluorophenyl)acetamide

Nom du produit:2-{[2-(azepan-1-yl)-6-methylpyrimidin-4-yl]oxy}-N-(4-chloro-2-fluorophenyl)acetamide

IUPAC Name:2-{[2-(azepan-1-yl)-6-methylpyrimidin-4-yl]oxy}-N-(4-chloro-2-fluorophenyl)acetamide

: CAS：1226427-48-0; Formule moléculaire：C19H22ClFN4O2; Pureté：95%+

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: N° CAS:1226427-48-0; Formule moléculaire:C19H22ClFN4O2; Point de fusion:-; Code SMILES:CC1=NC(=NC(OCC(=O)NC2=C(F)C=C(Cl)C=C2)=C1)N1CCCCCC1; Densité:

: Numéro de catalogue:CM838749; Poids moléculaire:392.86; Point d'ébullition:; N° Mdl:; Stockage:

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: Azepanes; The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.