Nom du produit:2,6-Difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
IUPAC Name:2,6-difluoro-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine
- CAS：1204333-58-3
- Formule moléculaire：C11H14BF2NO2
- Pureté：98%
- Numéro de catalogue：CM129669
- Poids moléculaire：241.04
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1204333-58-3
- Formule moléculaire:C11H14BF2NO2
- Point de fusion:-
- Code SMILES:CC1(C)C(C)(C)OB(C2=CC(F)=NC(F)=C2)O1
- Densité:
- Numéro de catalogue:CM129669
- Poids moléculaire:241.04
- Point d'ébullition:
- N° Mdl:MFCD12913987
- Stockage:
Category Infos
- Pyridines
- Pyridine is a six-membered heterocyclic compound containing one nitrogen heteroatom. Pyridine and piperidine are the most frequently occurring heterocyclic building blocks in drug molecules. According to incomplete statistics, there are currently more than 180 drugs containing pyridine or piperidine structure that have been marketed, nearly 1/5 of the drugs approved for marketing in recent years contain these two structures.
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- Pyridine is a basic heterocyclic organic compound with the chemical formula C5H5N. It is structurally related to benzene, with one methine group (=CH−) replaced by a nitrogen atom. It is a highly flammable, weakly alkaline, water-miscible liquid with a distinctive, unpleasant fish-like smell.
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Column Infos
- Naporafenib
- Erasca's Naporafenib receives FDA Fast Track Designation in combination with Trametinib (Mekinist) for the treatment of adult patients with advanced NRAS-mutated melanoma. Naporafenib has been dosed in over 500 patients to date, and has demonstrated preliminary evidence of its effectiveness. Naporafenib (LXH254) is an orally available pan-RAF inhibitor under development. It targets downstream BRAF and CRAF nodes, and has first-in-class and best-in-class potential in NRAS-mutated melanoma and other RAS/MAPK pathway-altered solid tumors.
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