Nom du produit:tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate
IUPAC Name:tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate
Product Overview |
Tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate is an organochlorine compound and a member of the pyridopyrimidine family. It is a white, crystalline solid with a molecular weight of 269.73 g/mol. Tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate has been studied extensively in recent years due to its potential applications in scientific research. |
Synthesis and Application |
Tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate can be synthesized via a multi-step process. The first step involves the condensation of 1-chloro-2-methyl-4-nitrobenzene with ethyl acetoacetate in the presence of sodium ethoxide in ethanol. This reaction yields a nitro-substituted intermediate, which is then reduced to the corresponding hydroxy compound. The hydroxy compound is then reacted with ethyl chloroformate to form the desired product, tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate. Tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate has been used in a wide range of scientific research applications. It has been employed as a catalyst in the synthesis of various compounds, such as quinolines, pyridines, and pyrimidines. It has also been used to study the mechanism of action of several drugs, such as the anti-inflammatory drug indomethacin. In addition, tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate has been used to study the mechanism of action of several enzymes, such as the enzyme acetylcholinesterase. |
Future Directions |
The potential applications of tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate are vast and there are several future directions that could be explored. One potential future direction is to further study the mechanism of action of tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate and its effects on various enzymes. Additionally, further research could be conducted to explore the potential applications of tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate in drug design and development. Another potential future direction is to study the effects of tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate on various physiological processes, such as inflammation and cardiovascular health. Finally, further research could be conducted to explore the potential of tert-butyl 2-chloro-5H,6H,7H,8H-pyrido[3,4-d]pyrimidine-7-carboxylate as a therapeutic agent for various diseases and disorders. |