Nom du produit:1-(azetidin-3-yl)-4-(3-(trifluoromethyl)phenyl)piperazine trihydrochloride

IUPAC Name:1-(azetidin-3-yl)-4-[3-(trifluoromethyl)phenyl]piperazine trihydrochloride

CAS:1184993-45-0
Formule moléculaire:C14H21Cl3F3N3
Pureté:95%
Numéro de catalogue:CM169714
Poids moléculaire:394.69

Unité d'emballage Stock disponible Prix($) Quantité
CM169714-1g in stock džŪȤȤ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1184993-45-0
Formule moléculaire:C14H21Cl3F3N3
Point de fusion:-
Code SMILES:FC(C1=CC(N2CCN(C3CNC3)CC2)=CC=C1)(F)F.[H]Cl.[H]Cl.[H]Cl
Densité:
Numéro de catalogue:CM169714
Poids moléculaire:394.69
Point d'ébullition:
N° Mdl:MFCD09751173
Stockage:Store at room temperature.

Category Infos

Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Azetidines
Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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