Nom du produit:N-Cyclopropyl-1-(1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carbonyl)piperidine-3-carboxamide hydrochloride

IUPAC Name:N-cyclopropyl-1-{1-methyl-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridine-3-carbonyl}piperidine-3-carboxamide hydrochloride

CAS:1160245-30-6
Formule moléculaire:C17H26ClN5O2
Pureté:97%
Numéro de catalogue:CM286814
Poids moléculaire:367.88

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CM286814-1g in stock ſƼƼ
CM286814-5g 1-2 Weeks ƼƤſ

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Détails du produit

N° CAS:1160245-30-6
Formule moléculaire:C17H26ClN5O2
Point de fusion:-
Code SMILES:O=C(C1CN(C(C2=NN(C)C3=C2CNCC3)=O)CCC1)NC4CC4.[H]Cl
Densité:
Numéro de catalogue:CM286814
Poids moléculaire:367.88
Point d'ébullition:
N° Mdl:
Stockage:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Pyrazolopyridines
Over the past few years, many pyrazole fused-ring systems, especially with applications in medicinal chemistry, have been published. These include general structures such as pyrazoline, pyrazoline, pyrazoquinoline, pyrazoloisoquinoline, pyrazoline, pyrazolopyrazine, pyrazolopyrazine, pyranopyrazole, pyrano Pyrazoles, pyrazolotriazines and pyrazole fused phosphorus rings.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.