Nom du produit:4-(6-((4-(Methylsulfonyl)piperazin-1-yl)methyl)-2-(2-(tetrahydro-2H-pyran-2-yl)-2H-indazol-4-yl)thieno[3,2-d]pyrimidin-4-yl)morpholine
IUPAC Name:4-{6-[(4-methanesulfonylpiperazin-1-yl)methyl]-4-(morpholin-4-yl)thieno[3,2-d]pyrimidin-2-yl}-2-(oxan-2-yl)-2H-indazole
- CAS：1146955-37-4
- Formule moléculaire：C28H35N7O4S2
- Pureté：95%+
- Numéro de catalogue：CM336101
- Poids moléculaire：597.75
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:1146955-37-4
- Formule moléculaire:C28H35N7O4S2
- Point de fusion:-
- Code SMILES:O=S(N(CC1)CCN1CC2=CC3=C(C(N4CCOCC4)=NC(C5=CC=CC6=NN(C7OCCCC7)C=C56)=N3)S2)(C)=O
- Densité:
- Numéro de catalogue:CM336101
- Poids moléculaire:597.75
- Point d'ébullition:
- N° Mdl:
- Stockage:2-8°C
Category Infos
- Piperazines
- Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
- Indazoles
- Indazoles are a class of organic heterocyclic compounds, also known as 1,2-diazaindene and benzopyrazole. Indazole is a good bioisomer of phenol, which is more lipophilic than phenol and less prone to phase I and II metabolism. Indazole derivatives have a wide range of biological activities, and it has been confirmed that indazole compounds have anti-tumor, analgesic, anti-inflammatory and other drug activities. Anticancer is the most important application field of indazole drugs. Renal cell carcinoma, solid tumor, nausea and vomiting caused by chemotherapy and leukemia are the main indications of this structural backbone drug.
- Thienopyrimidines
- Thienopyrimidines are a class of heterocyclic compounds with diverse biological activities depending on their detailed substitution patterns. In addition, many thienopyrimidine derivatives have shown potent activity against cancer cell lines and specific oncogenes.
- Tetrahydropyrans
- Tetrahydropyran is an organic compound consisting of a saturated six-membered ring containing five carbon atoms and one oxygen atom. Tetrahydropyrans are common structural motifs in natural products and synthetic therapeutic molecules. In nature, these six-membered oxygen heterocycles are usually assembled by intramolecular reactions, including oxygen Michael addition or ring opening of epoxy alcohols. In fact, polyether natural products have been particularly extensively studied for their fascinating structures and important biological properties; these are often formed through endoselective epoxy open cascades.
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