Nom du produit:2-Chloro-4-fluorobromobenzene
IUPAC Name:1-bromo-2-chloro-4-fluorobenzene
- CAS：110407-59-5
- Formule moléculaire：C6H3BrClF
- Pureté：95+%
- Numéro de catalogue：CM247719
- Poids moléculaire：209.44
Pour une utilisation en R&D uniquement..
Détails du produit
- N° CAS:110407-59-5
- Formule moléculaire:C6H3BrClF
- Point de fusion:-
- Code SMILES:BrC1=C(C=C(C=C1)F)Cl
- Densité:
- Numéro de catalogue:CM247719
- Poids moléculaire:209.44
- Point d'ébullition:196.3°C at 760 mmHg
- N° Mdl:MFCD00142587
- Stockage:Store at room temperature.
Category Infos
- Benzenes
- Benzene is an important organic compound with the chemical formula C6H6, and its molecule consists of a ring of 6 carbon atoms, each with 1 hydrogen atom. Benzene is a sweet, flammable, colorless and transparent liquid with carcinogenic toxicity at room temperature, and has a strong aromatic odor. It is insoluble in water, easily soluble in organic solvents, and can also be used as an organic solvent itself. The ring system of benzene is called benzene ring, and the structure after removing one hydrogen atom from the benzene ring is called phenyl. Benzene is one of the most important basic organic chemical raw materials. Many important chemical intermediates can be derived from benzene through substitution reaction, addition reaction and benzene ring cleavage reaction.
Column Infos
- Casdatifan
- Casdatifan (AB521) is a small molecule inhibitor of the oxygen-sensing transcription factor HIF-2⍺ that has demonstrated potent antitumor activity in xenograft models of renal cell cancer (RCC). Under normal physiological conditions, HIF-2⍺ is involved in sensing oxygen availability in multiple organs. In certain tumors, particularly clear cell RCC (ccRCC), HIF-2⍺ activity is highly dysregulated as a result of genetic abnormalities in the VHL pathway. This creates a situation of pseudohypoxia and the abnormal increase in HIF-2⍺-mediated expression of a wide array of proteins involved in cancer cell proliferation and survival, treatment resistance and angiogenesis.
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