Nom du produit:3-Cyclopropyl-1-(4-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

IUPAC Name:3-cyclopropyl-1-(4-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid

CAS:1011397-26-4
Formule moléculaire:C20H14FN3O2S
Pureté:95%+
Numéro de catalogue:CM272090
Poids moléculaire:379.41

Unité d'emballage Stock disponible Prix($) Quantité
CM272090-1g 1-2 Weeks ǶƎŵ
CM272090-5g 1-2 Weeks ưȡũ

Pour une utilisation en R&D uniquement..

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Détails du produit

N° CAS:1011397-26-4
Formule moléculaire:C20H14FN3O2S
Point de fusion:-
Code SMILES:O=C(C1=C2C(N(C3=CC=C(F)C=C3)N=C2C4CC4)=NC(C5=CC=CS5)=C1)O
Densité:
Numéro de catalogue:CM272090
Poids moléculaire:379.41
Point d'ébullition:
N° Mdl:MFCD09473375
Stockage:

Category Infos

Thiophenes
Thiophene is a five-membered heterocyclic compound containing a sulfur heteroatom with the molecular formula C4H4S. Thiophene is aromatic and is very similar to benzene; electrophilic substitution reaction is easier than benzene, and it is mainly substituted at the 2-position. Thiophene ring system has certain stability to oxidant.
Pyrazolopyridines
Over the past few years, many pyrazole fused-ring systems, especially with applications in medicinal chemistry, have been published. These include general structures such as pyrazoline, pyrazoline, pyrazoquinoline, pyrazoloisoquinoline, pyrazoline, pyrazolopyrazine, pyrazolopyrazine, pyranopyrazole, pyrano Pyrazoles, pyrazolotriazines and pyrazole fused phosphorus rings.
Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.