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Aficamten

Evaluate Pharma recently issued an article listing "the most valuable potential drugs currently under development", and Aficamten is one of them. Aficamten is a novel cardiac myosin inhibitor for the treatment of hypertrophic cardiomyopathy, which achieves its therapeutic effect by reducing the hypercontractility of obstructive HCM and improving diastolic function.

1-methyl-1H-pyrazole-4-carboxylic acid
1-methyl-1H-pyrazole-4-carboxylic acid
CM104666
5952-92-1
(R)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride
(R)-5-Bromo-2,3-dihydro-1H-inden-1-amine hydrochloride
CM249454
1443238-61-6
(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-amine
(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-amine
CM1046485
2364560-36-9
(R)-tert-Butyl (5-bromo-2,3-dihydro-1H-inden-1-yl)carbamate
(R)-tert-Butyl (5-bromo-2,3-dihydro-1H-inden-1-yl)carbamate
CM270391
903555-98-6
tert-butyl N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]carbamate
tert-butyl N-[(1R)-5-(5-ethyl-1,2,4-oxadiazol-3-yl)-2,3-dihydro-1H-inden-1-yl]carbamate
CM1046484
2364560-34-7
tert-butyl N-[(1R)-5-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl]carbamate
tert-butyl N-[(1R)-5-(N-hydroxycarbamimidoyl)-2,3-dihydro-1H-inden-1-yl]carbamate
CM1046483
2364560-04-1
(R)-tert-Butyl (5-cyano-2,3-dihydro-1H-inden-1-yl)carbamate
(R)-tert-Butyl (5-cyano-2,3-dihydro-1H-inden-1-yl)carbamate
CM270392
903555-99-7