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(1R,5S)-3-{7-[8-ethyl-7-fluoro-3-(methoxymethoxy)naphthalen-1-yl]-8-fluoro-2-(methylsulfanyl)pyrido[4,3-d]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octane

(1R,5S)-3-{7-[8-ethyl-7-fluoro-3-(methoxymethoxy)naphthalen-1-yl]-8-fluoro-2-methanesulfonylpyrido[4,3-d]pyrimidin-4-yl}-3,8-diazabicyclo[3.2.1]octane

tert-butyl (1R,5S)-3-(2-{2-[(2S)-1-{4-[2-(tert-butoxy)-2-oxoethoxy]butyl}pyrrolidin-2-yl]ethyl}-7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoropyrido[4,3-d]pyrimidin-4-yl)-3,8-diazabicyclo[3.2.1]octane-8-carboxylate

2-{4-[(2S)-2-(2-{4-[(1R,5S)-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoropyrido[4,3-d]pyrimidin-2-yl}ethyl)pyrrolidin-1-yl]butoxy}acetic acid

2-{4-[(2S)-2-(2-{4-[(1R,5S)-8-[(tert-butoxy)carbonyl]-3,8-diazabicyclo[3.2.1]octan-3-yl]-7-(8-ethyl-7-fluoro-3-hydroxynaphthalen-1-yl)-8-fluoropyrido[4,3-d]pyrimidin-2-yl}ethyl)pyrrolidin-1-yl]butoxy}acetic acid

5,7-dichloro-8-fluoro-2-methyl-1H-pyrido[4,3-d]pyrimidin-4-one

8-chloro-1H-pyrido[3,4-d]pyrimidine-2,4-dione

8-bromo-2-chloro-pyrido[4,3-d]pyrimidine

5-fluoro-6-methoxy-3H-pyrido[3,4-d]pyrimidin-4-one

2,4,7-trichloro-8-fluoro-5-methoxy-pyrido[4,3-d]pyrimidine

5,7-dichloro-2-(difluoromethyl)-8-fluoro-1H-pyrido[4,3-d]pyrimidin-4-one

2,5,7-trichloro-8-fluoro-3H-pyrido[4,3-d]pyrimidin-4-one

5,7-dichloro-8-fluoro-1H-pyrido[4,3-d]pyrimidin-4-one

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4,6-Dichloro-1-methylpyrido[3,2-d]pyrimidin-2(1H)-one