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Oxiranes

Oxirane is a three-membered ring compound consisting of one oxygen atom and two carbon atoms. Oxirane is present in natural products such as cryptocin, which has anticancer properties, and azidomycin, trienone, and epoxidomycin, which have shown activity against drug-resistant leukemias and AIDS-related lymphomas. Other oxirane containing bioactive molecules have anti-inflammatory, immunosuppressive, and antitumor activities. Oxiranes are a strained ring susceptible to various nucleophilic, ring-opening or rearrangement reactions, so they are considered to be one of the most important intermediates in organic synthesis.

1,3,5-Tris((R)-oxiran-2-ylmethyl)-1,3,5-triazinane-2,4,6-trione

1-Phenyl-7-oxabicyclo[4.1.0]heptane

3'-Phenylspiro[indene-2,2'-oxiran]-1(3H)-one

tert-Butyl methyl(3-(oxiran-2-yl)propyl)carbamate

4-(4-(Oxiran-2-ylmethoxy)phenyl)-1,2,3-thiadiazole

(S)-2-((2-(Allyloxy)phenoxy)methyl)oxirane

1-(Oxiran-2-ylmethyl)-4-phenylpiperazine

2-(6-Oxabicyclo[3.1.0]hexan-2-ylidene)malononitrile

1-((2-(2,4-Dichlorophenyl)oxiran-2-yl)methyl)-1H-imidazole

7-Oxabicyclo[4.1.0]heptane-2-carboxylic acid

Methyl 7-oxabicyclo[4.1.0]hept-3-ene-3-carboxylate

((2S,3R)-3-((Benzyloxy)methyl)oxiran-2-yl)methyl 4-nitrobenzoate

Ethyl octahydrospiro[4,7-methanoindene-5,2'-oxirane]-3'-carboxylate

(2R,3S)-3-Phenyloxirane-2-carboxylic acid

N,N-Diisopropyl-3-(oxiran-2-yl)-2-phenylquinoline-4-carboxamide

2-Ethyl-3-(3-ethyl-5-(4-ethylphenoxy)pentyl)-2-methyloxirane

Allyl 4-methyl-7-oxabicyclo[4.1.0]heptane-3-carboxylate

[(2S,3S)-3-[(1S)-1-(methoxymethoxy)ethyl]oxiran-2-yl]methanol

(2R,3S)-3-[(1S)-1-(methoxymethoxy)ethyl]oxirane-2-carbaldehyde

(2R)-2-[(1S)-1-[(4-methoxyphenyl)methoxy]prop-2-en-1-yl]oxirane

2-(3-acetyloxiran-2-yl)-6-chloro-N-phenylbenzamide

Methyl R-(+)-3,4-epoxybutyrate

rel-(2S)-2-[(1R)-1-bromoethyl]oxirane

(2R)-2-[(1R)-1-bromoethyl]oxirane