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Isoxazoles

Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.

3,5-Dimethylisoxazole-4-boronic acid

3-Hydroxymethyl-5-methylisoxazole

3-(2-Chlorophenyl)-5-isoxazolemethanol

(3-(4-Fluorophenyl)isoxazol-5-yl)methanol

(3-(o-Tolyl)isoxazol-5-yl)methanol

(5-Methylisoxazol-4-yl)methanol

3-methylisoxazole-5-carboxylic acid

1,2-oxazol-3-ylmethanol

3-[(4-methoxyphenyl)methoxy]-1,2-oxazole-5-carboxylic acid

3,5-dimethyl-4-(tetramethyl-1,3,2-dioxaborolan-2-yl)-1,2-oxazole

4-bromo-3,5-dimethyl-1,2-oxazole

1,2-oxazol-3-amine

4-(chloromethyl)-5-cyclopropyl-3-(2,6-dichlorophenyl)-1,2-oxazole

ethyl 1,2-oxazole-3-carboxylate

ethyl 1,2-oxazole-4-carboxylate

(1,2-oxazol-3-yl)methanamine hydrochloride

5-tert-butyl-1,2-oxazol-3-amine

1,2-oxazole-3-carbonitrile

1,2-oxazol-3-ylmethanamine

3-(4-bromophenyl)isoxazole

5-(4-methylphenyl)-1,2-oxazole

1,2-oxazole-3-carbaldehyde

3-Ethylisoxazol-5-amine

N-Methyl-1-(5-phenylisoxazol-3-yl)methanamine hydrochloride